- The Chicago White Sox activated left-hander Chris Sale from the 15-day DL and designated right-hander Frank Francisco for assignment, according to a team announcement. Sale allowed one hit over six shutout innings in his return.
- The Tampa Bay Rays activated right-hander Alex Cobb from the 15-day DL and optioned Kevin Kiermaier to Triple-A Durham, the team announced. Cobb went 6.2 scoreless innings in the Rays' extra-inning victory on Friday.
- The San Francisco Giants placed right-hander Santiago Casilla on the 15-day DL with a strained right hamstring and recalled George Kontos from Triple-A Fresno, the team announced.
- The Pittsburgh Pirates activated catcher Russell Martin from the 15-day DL and designated left-hander Wandy Rodriguez for assignment, per a team announcement.
- The Cleveland Indians placed right-hander Zach McAllister on the 15-day DL with a low back strain and transferred center fielder Nyjer Morgan from the 15-day DL to the 60-day DL. (Via Indians Twitter account)
- The Baltimore Orioles placed right-hander Tommy Hunter on the 15-day DL, retroactive to May 21, with a left groin strain and recalled Preston Guilmet from Triple-A Norfolk, the team announced.
- The San Diego Padres placed left-hander Robbie Erlin on the 15-day DL, retroactive to May 18, with left eblow soreness, and purchased the contract of Blaine Boyer from Triple-A El Paso. (Via Padres Twitter account)
- The Washington Nationals optioned Ryan Mattheus to Triple-A Syracuse and recalled right-hander Blake Treinen from Triple-A, per a team announcement. Treinen allowed a pair of runs in 5.2 innings in the Nats' loss on Thursday.
- The Los Angeles Dodgers released catcher Miguel Olivo after he bit off part of Triple-A teammate Alex Guerrero's ear. (Via Dodgers Twitter account)
- The Miami Marlins purchased the contract of Chris Hatcher from Triple-A New Orleans and optioned Anthony De Sclafani down to Triple-A. The team also transferred Rafael Furcal from the 15-day DL to the 60-day DL. (Via Marlins Twitter account)
- The Kansas City Royals optioned Mike Moustakas to Triple-A Omaha and will recall Jimmy Paredes on Friday, according to a team announcement.
- The Indians purchased the contract of Mark Lowe from Triple-A Columbus, recalled T.J. House and optioned Kyle Crockett down to Triple-A. (Via Indians Twitter account)
- The Pittsburgh Pirates claimed right-hander Josh Wall off waivers from the Los Angeles Angels, the team announced.