UPDATE: Manny Ramirez was scrated from tonight's lineup and will make his debut tomorrow. He still may get a pinch hit at-bat, but otherwise we will see him tomorrow.
New White Sox designated hitter Manny Ramirez will make his debut tonight versus his original franchise, the Cleveland Indians. Ramirez has not played in Cleveland since the 2008 season, but he received his fair share of boos then, and he will definitely receive plenty tonight.
The Indians are 22.0 games out of first place so it is not like this matchup holds any major significance for them in terms of the standings. However, the White Sox are four games out of first so they could really make it difficult for them to get back in it entering September if they can have a big series.
Ramirez is a career .312 hitter in Progressive Field (1,768 ABs), so he is obviously very comfortable in his first ballpark.